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HIV Drugs
Our product range includes a wide range of tenofovir disoproxil fumarate, abacavir sulfate, atazanavir sulfate and lamivudine.
Tenofovir Disoproxil Fumarate
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Product Details:
| Manufacturer | Parad Pharmacceuticals |
| Strength | 300 mg |
- HIV-1 Treatment: TDF is used in combination with other antiretroviral medicines to treat HIV-1 in adults and children (aged 2 years and older, weighing at least 10 kg).
- Chronic Hepatitis B Treatment: It is approved for treating chronic HBV infection in adults and pediatric patients.
- HIV-1 Prevention (PrEP): TDF is used as part of HIV pre-exposure prophylaxis (PrEP) to reduce the risk of HIV-1 transmission in high-risk individuals.
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Abacavir Sulfate
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Product Details:
| Strength | 300 mg |
- HIV-1 Treatment: Indicated for the treatment of HIV-1 infection in combination with other antiretroviral agents.
- Patient Population: Approved for use in adults and children 3 months and older.
- Usage Context: It is generally used as part of combination therapy (ART), often in fixed-dose combinations with other drugs like lamivudine.
- Mechanism of Action: Intracellularly, it is converted to its active metabolite, carbovir triphosphate, which terminates viral DNA growth.
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Atazanavir Sulfate
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Product Details:
| Strength | 300 mg |
- HIV-1 Treatment: Used as part of highly active antiretroviral therapy (HAART) to reduce viral load.
- Boosted Regimens: Frequently combined with other (100 mg) to enhance pharmacokinetic properties, particularly in treatment-experienced patients.
- Formulation: Available as capsules and tablets (commonly 300 mg/100 mg with ritonavir).
- Pharmacokinetics: Generally taken with food to improve absorption.
- Administration: It acts by targeting and inhibiting HIV-1 protease, which is necessary for the processing of viral Gag and Gag-Pol polyproteins.
- Safety Profile: Generally well-tolerated compared to other protease inhibitors, but is not a cure for HIV/AIDS.
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Lamivudine
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Product Details:
| Strength | 150,300 mg |
- HIV-1 Treatment: Used in combination with other antiretroviral agents to suppress HIV replication, increasing CD4+ cell counts and delaying AIDS-related illnesses.
- Hepatitis B (HBV) Treatment: Used to treat chronic HBV infection, often as monotherapy, by inhibiting the hepatitis B DNA polymerase, thus reducing liver damage.
- Mechanism of Action: As a prodrug, lamivudine is phosphorylated intracellulary to active lamivudine triphosphate, which acts as a chain terminator during reverse transcription of viral RNA to DNA.
- Administration: Available as oral tablets and liquid solutions, commonly taken once or twice daily.
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